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Japan’s Ministry of Education, Culture, Sports, Science and Technology (MEXT) recently selected the
Institute for the Advanced Study of Human Biology (ASHBi) for participation in the World Premier
International Research Center (WPI) Program, establishing it within Kyoto University Institute for
Advanced Study (KUIAS) on 30 October 2018 with Mitinori Saitou, a world-leading developmental biologist,
at its head. ASHBi is now looking for a Program-Specific Researcher (Postdoctoral Fellow) in the laboratory
of Associate Professor Ryo Yamamoto (Stem Cell Biology/Hematology Group). Details as follows.
1. Job Titles：
Program-Specific Researcher (Postdoctoral Fellow)
2. Number of Positions：
One (1)
3. Affiliation：
Institute for the Advanced Study of Human Biology (ASHBi), KUIAS Kyoto University
Yoshida Konoe-cho, Sakyo, Kyoto 606-8501 Japan
4. Eligibility：
Essential requirements are as follows:
1. The candidate has a Ph.D.
2. The candidate has excellent research achievements in the related fields and ability to supervise
postdoctoral fellows and graduate students
3. The candidate should have the ability to develop and manage his/her research projects
5. Starting Date:
April 1, 2023 or the earliest possible date thereafter (adjustable according to individual requirements)
6. Term:
From the day you take the position (negotiable) to March 31, 2024.
In and after the following year, the contract can be renewed annually depending on achievements until
March 31,2025.
Initial probationary employment period: six (6) months

7. Job Descriptions:
ASHBi will investigate the core concepts of human biology with a focus on genome regulation and
disease modeling, creating a foundation of knowledge for developing innovative and unique humancentric therapies. The key goals are: 1) to achieve outstanding research in key individual themes in
human biology in the area of reproduction, development, growth and aging as well as heredity and
evolution; 2) to elucidate the principles for the emergence of species differences among humans, nonhuman primates, and rodents for proper extrapolation of the findings in model organisms to humans; 3)
to generate primate models for key gene functions and intractable diseases; 4) to reconstitute key
human cell lineages and tissues in vitro and validate their properties based on integrative information;
and 5) to contribute to formalize an ethics for the use of human/non-human primate materials and
create a philosophy to direct the values of the Institute’s research outcomes.
The institute is seeking suitable candidates for Program-Specific Researcher (Postdoctoral Fellow) to
accelerate its mission. Stem Cell Biology/Hematology group (R. Yamamoto group) will perform
transcriptome, epigenome, and functional analysis of mouse/human/macaque primary cells
(hematopoietic stem cells). The candidate is expected to perform high-level research and act as the leading
researcher in human biology and the related fields.
1) To elucidate mechanisms of hematopoietic stem cells
2) To elucidate mechanisms of aging in hematopoietic stem cells
3) To elucidate mechanisms of hematological malignancies
4) To perform single cell analysis and bioinformatic analysis
5) To establish mouse/human/cynomolgus model in hematological research
8. Working Conditions:
Five (5) working days per week (days off: Saturdays, Sundays, public holidays, year-end and New Year
holidays, and Foundation Day, as per University guidelines)
Working hours: 38 hours 45 minutes per week under a discretionary labor system